STRAIN STREPTOMYCES NODOSUS 472 VNIISCHM D-666 AS PRODUCER OF AMPHOTERICIN B

FIELD: microbiology, antibiotics. SUBSTANCE: strain Strepromyces nodosus 472 VNIISCHM D-666 is obtained by selection method by effect with mutagens N-nitrosomethylurea and N-nitroso-N-methylbiuret. Strain shows the enhanced productivity of amphotericin B that is effective antifungal antibiotic used...

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Hauptverfasser: PRONINA M.I, FADEEVA I.P, DOLINOVA O.I, POLATOVSKAJA O.G, KAMINSKAJA A.JU, MALKOV M.A
Format: Patent
Sprache:eng
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Zusammenfassung:FIELD: microbiology, antibiotics. SUBSTANCE: strain Strepromyces nodosus 472 VNIISCHM D-666 is obtained by selection method by effect with mutagens N-nitrosomethylurea and N-nitroso-N-methylbiuret. Strain shows the enhanced productivity of amphotericin B that is effective antifungal antibiotic used in medicinal practice for treatment of deep and systemic mycosis. EFFECT: increased yield of amphotericin B.