METHOD FOR OBTAINING HYPERIMMUNE ANTIRABIC SERA

FIELD: veterinary virology. SUBSTANCE: method is carried out by a 5-fold immunization of sheep with inactivated virus of rabies. Immunization is conducted for 3-42 points at 14-d-long interval. The method enables to obtain ovine blood sera at the titers of antibodies in the test of fluorescence foca...

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Hauptverfasser: SLIVKO I.A, GRUZDEV K.N, LUNITSIN A.V, NEDOSEKOV V.V, KURINNOV V.V
Format: Patent
Sprache:eng
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Zusammenfassung:FIELD: veterinary virology. SUBSTANCE: method is carried out by a 5-fold immunization of sheep with inactivated virus of rabies. Immunization is conducted for 3-42 points at 14-d-long interval. The method enables to obtain ovine blood sera at the titers of antibodies in the test of fluorescence focal inhibition being 1: 10240-20480, and 1:16-32 in reaction of diffuse precipitation. The method favors to obtain efficiently and safely hyperimmune antirabic sera of high virus-neutralizing and precipitating activity. EFFECT: higher efficiency. 1 ex, 2 tbl