APPLICATION OF 5-ETHYNYLURACIL AS AN ACTIVATOR OF URACIL-REDUCTASE, PHARMACEUTICAL COMPOSITION, METHOD FOR ITS OBTAINING, PHARMACEUTICAL COMPOSITION FOR INCREASING THE ACTION OR DECREASING THE TOXICITY OF 5-FLUOURACIL

FIELD: pharmaceutics. SUBSTANCE: it is suggested a new inactivator of uracil-reductase - 5-ethynyluracil. It enhances the action of 5-fluouracil and is used in treating the cancer. It is, also, suggested to apply pharmaceutical composition based upon 5-ethynyluracil and the method for its obtaining....

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Hauptverfasser:	PORTER DEHVID DZHON TIMOTI, RAKHIM SAAD DZHORDZH, SPEKTOR TOMAS
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY DERIVATIVES THEREOF HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS
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Beschreibung
Zusammenfassung:	FIELD: pharmaceutics. SUBSTANCE: it is suggested a new inactivator of uracil-reductase - 5-ethynyluracil. It enhances the action of 5-fluouracil and is used in treating the cancer. It is, also, suggested to apply pharmaceutical composition based upon 5-ethynyluracil and the method for its obtaining. Pharmaceutical combination is suggested to enhance the action or decrease the toxicity of 5- fluouracil. Such a combination contains separate or mixed components of 5-ethyluracil and 5-fluouracil or its promedicine for simultaneous, separate or successive injection. EFFECT: increased number of activators. 16 cl, 2 dwg, 8 ex, 1 tbl