METHOD OF SYNTHESIS OF 2,5,8-TRIHYDROXY-6,7-DICHLORO-3-ETHYL-1,4-NAPHTHOQUINONE

METHOD OF SYNTHESIS OF 2,5,8-TRIHYDROXY-6,7-DICHLORO-3-ETHYL-1,4-NAPHTHOQUINONE

FIELD: organic chemistry, chemical technology. SUBSTANCE: invention relates to the improved method of synthesis of 2,5,8-trihydroxy-6,7-dichloro-1,4-naphthoquinone by cycloacylation of 1,2,4-trimethoxy-3,5-diethyl- -benzene with dichloromaleic anhydride in the presence of aluminum chloride and sodiu...

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Bibliographische Detailangaben
Hauptverfasser: BALANEVA N.N, POKHILO N.D, ANUFRIEV V.F, MALINOVSKAJA G.V, CHIZHOVA T.L
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Zusammenfassung:FIELD: organic chemistry, chemical technology. SUBSTANCE: invention relates to the improved method of synthesis of 2,5,8-trihydroxy-6,7-dichloro-1,4-naphthoquinone by cycloacylation of 1,2,4-trimethoxy-3,5-diethyl- -benzene with dichloromaleic anhydride in the presence of aluminum chloride and sodium chloride. 1,2,4-Trimethoxy-3,5-diethylbenzene is synthesized by reduction of 3,5-diacetyl-1,2,4-trihydroxybenzene to 1,2,4-trihydroxy-3,5- diethylbenzene and its the following exhaustive methylation. Method provides preparing the end substance with yield 59% and excludes the use of fire hazard reagents used in synthesis of the parent compound. EFFECT: improved method of synthesis. 5 sch