SOLID MEDICINAL FORM OF ANTIULCER AGENT
FIELD: medicine, gastroenterology, pharmacy. SUBSTANCE: invention relates to pharmaceutical preparations used in treatment of stomach and duodenum ulcer disease, Zollinger-Ellison syndrome, reflux esophagitis. Invention involves development of solid medicinal form that comprises ranitidine as active...
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Zusammenfassung: | FIELD: medicine, gastroenterology, pharmacy. SUBSTANCE: invention relates to pharmaceutical preparations used in treatment of stomach and duodenum ulcer disease, Zollinger-Ellison syndrome, reflux esophagitis. Invention involves development of solid medicinal form that comprises ranitidine as active component and the following special accessory components: microcrystalline cellulose, low-molecular polyvinyl-pyrrolidone, stearic acid or its salts and modified starch or croscarmellose taken in the definite ratio of components. Composition with the claimed ratio of components provides optimal physical-chemical and technological properties of medicinal form and high bioavailability of medicinal substance. EFFECT: improved and valuable properties of drug. 6 cl, 1 ex |
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