PHARMACEUTICAL COMPOSITIONS COMPRISING DERIVATIVES OF HYDROXAMIC ACID

organic chemistry, pharmacy. SUBSTANCE: invention relates to a novel agent and pharmaceutical compositions based on thereof use for protection of mitochondrial genome and/or mitochondrions against damages or for treatment of diseases associated with these damages. An active component of the above-me...

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Bibliographische Detailangaben
Hauptverfasser:	SHUMEGI BALAZH, MARESKA BRUNO, LITERATI NAD' PETER, VIG LASLO
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	organic chemistry, pharmacy. SUBSTANCE: invention relates to a novel agent and pharmaceutical compositions based on thereof use for protection of mitochondrial genome and/or mitochondrions against damages or for treatment of diseases associated with these damages. An active component of the above-mentioned compositions is a derivative of hydroxamic acid of the formula (I) or its pharmaceutically acceptable acid-additive salt. Early this substance has been used for treatment of diabetes mellitus. Invention proposes an agent for treatment of myopathy and/or cardiomyopathy, or neurodegenerative diseases with a novel mechanism of action. EFFECT: new agent indicated above, valuable medicinal properties. 14 cl, 7 tbl, 7 test