CRYSTALLINE MODIFICATIONS OF 2-AMINO-4-(4-FLUORO- -BENZYLAMINO)-1-ETHOXYCARBONYLAMINOBENZENE AND METHOD OF THEIR PREPARING (VARIANTS)
organic chemistry, medicine, pharmacy. SUBSTANCE: invention describes 2-amino-4-(4-fluorobenzylamino)-1-ethoxycarbonylaminobenzene of the formula (I) as crystalline modifications A, B and C. Each modification shows a diffraction roentgenogram with reflexes no coinciding with reflexes of two other mo...
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Zusammenfassung: | organic chemistry, medicine, pharmacy. SUBSTANCE: invention describes 2-amino-4-(4-fluorobenzylamino)-1-ethoxycarbonylaminobenzene of the formula (I) as crystalline modifications A, B and C. Each modification shows a diffraction roentgenogram with reflexes no coinciding with reflexes of two other modifications. Crystalline modifications A, B, C are designated for preparing pharmaceutical compositions with anticonvulsive, antipyretic and analgetic effect. Invention describes also methods of preparing the indicated modifications. EFFECT: improved method of preparing, valuable medicinal properties of compositions. 13 cl, 5 dwg |
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