METHOD OF ISOLATION OF AVERMECTIN COMPLEXES

METHOD OF ISOLATION OF AVERMECTIN COMPLEXES

biotechnology, microbiology. SUBSTANCE: invention relates to the microbiological synthesis and isolation of avermectins from biomass of actinomycete Streptomyces avermitilis used for antiparasiting preparations preparing. Method involves extraction of avermectins from biomass of S. avermitilis, puri...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: MOSIN V.A, NOVIK T.S, KRUGLJAK E.B, DRINJAEV V.A
Format: Patent
Sprache:eng ; rus
Schlagworte:
BEER
BIOCHEMISTRY
CHEMISTRY
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
PROCESSES USING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Beschreibung
Zusammenfassung:biotechnology, microbiology. SUBSTANCE: invention relates to the microbiological synthesis and isolation of avermectins from biomass of actinomycete Streptomyces avermitilis used for antiparasiting preparations preparing. Method involves extraction of avermectins from biomass of S. avermitilis, purification of extract, separation of lipid fraction and isolation of the end product. Extraction of avermectins from biomass is carried out with a mixture consisting of water and low- and high-boiling solvents mixing with water in unlimited ratio. The proposed method ensures to isolate avermectin complexes with different content of individual avermectins showing the biological activity. EFFECT: improved method of isolation. 5 cl, 5 tbl, 5 ex