METHOD TO OBTAIN INJECTION PREPARATION BASED UPON A SUBSTANCE OF P-VITAMIN ACTIVITY
medicine, chemicopharmaceutical industry. SUBSTANCE: the method deals with dissolving quercetin in water to conduct injections at 75-85 C at the presence of sodium tetraborate and trilon B, cooling the solution obtained, filtration and ampoulating process followed by ampoules' sterilization. Qu...
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Zusammenfassung: | medicine, chemicopharmaceutical industry. SUBSTANCE: the method deals with dissolving quercetin in water to conduct injections at 75-85 C at the presence of sodium tetraborate and trilon B, cooling the solution obtained, filtration and ampoulating process followed by ampoules' sterilization. Quercetin, sodium tetraborate, polyvinylpyrrolidone and trilon B are applied at the following ratio, weight%: 1 : (0.7-1.0) : (5.5-8.0) : (0.01-0.015), correspondingly. The method enables to obtain injection solution of difficultly soluble substance. EFFECT: higher quality level, stability and bioavailability of injection solution. 2 tbl |
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