COMPOSITIONS AND METHODS OF GENETIC MATERIAL DELIVERY

medicine, medicinal genetics. SUBSTANCE: method involves introduction of genetic material with enhancer of polynucleotide function (for example, bupivacaine) in cells of individual person. Molecules of nucleic acid no containing retrovirus particles are incorporated also. Nucleic acid molecule has t...

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Hauptverfasser: VILL'JAM V. VILL'JAMS, BIN VANG, MAJKL DZH. MERVA, LESLI R. KONI, VINSENT R. ZURAVSKI ML, DEHVID B. VEJNER
Format: Patent
Sprache:eng
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Zusammenfassung:medicine, medicinal genetics. SUBSTANCE: method involves introduction of genetic material with enhancer of polynucleotide function (for example, bupivacaine) in cells of individual person. Molecules of nucleic acid no containing retrovirus particles are incorporated also. Nucleic acid molecule has the sequence that encodes protein which involves at least one epitope identical or similar with antigen epitope being the latter is a target for immune response. This nucleotide sequence is bound operatively with regulatory sequences. Invention describes also a pharmaceutical composition and set for method realization. EFFECT: broadened arsenal of agents against HIV infection. 48 cl, 1 tbl, 19 dwg, 59 ex