INACTIVATED VACCINE AGAINST QUERY FEVER
medicinal microbiology, vaccines and sera production. SUBSTANCE: invention proposes vaccine containing three components: corpuscular antigen from Bernet's coxiellas, 0.25-0.50 mcg; Bernet's coxiella corpuscular antigen treated with chloroform and methanol, 0.15-0.30 mcg; Bernet's coxi...
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Zusammenfassung: | medicinal microbiology, vaccines and sera production. SUBSTANCE: invention proposes vaccine containing three components: corpuscular antigen from Bernet's coxiellas, 0.25-0.50 mcg; Bernet's coxiella corpuscular antigen treated with chloroform and methanol, 0.15-0.30 mcg; Bernet's coxiella corpuscular antigen prepared by treatment of corpuscular antigen with trichloroacetic acid, 5.00-10.00 mcg. Strain Luga-1 is used as vaccine strain of Bernet's coxiellas. EFFECT: high resistance against query fever pathogen, minimal doses of components, maximal immunobiological safety. 1 tbl |
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