PHOTOSENSITIZER FOR PHOTODYNAMIC THERAPY

physiotherapeutic methods. SUBSTANCE: photosensitizer is water-soluble derivative of tetraazaporphyrin titanyl complexes with general formula RnLTiO, wherein L is ligand selected from group including phthalocyanine, naphthalocyanine, and tetrapyrazinoporphyrazine; R is water-solubilization hydrophil...

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Hauptverfasser:	JUZHAKOVA O.A, MEEROVICH G.A, ULANOVA L.A, TORSHINA N.L, LUK'JANETS E.A, KALIJA O.L, VOROZHTSOV G.N, NEGRIMOVSKIJ V.M, LUZHKOV JU.M, KUZNETSOVA N.A, PYKHTINA E.V, KOVALEVA M.A
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	physiotherapeutic methods. SUBSTANCE: photosensitizer is water-soluble derivative of tetraazaporphyrin titanyl complexes with general formula RnLTiO, wherein L is ligand selected from group including phthalocyanine, naphthalocyanine, and tetrapyrazinoporphyrazine; R is water-solubilization hydrophilic substituent; and n = 3-10. Novel photosensitizers show high efficiency in multivariable effect on deep tumor tissues and other pathologic neoplasms under hypoxia conditions. EFFECT: enhanced therapeutic efficiency. 2 tbl, 7 ex