ACYL DERIVATIVES OF GUANOSINE, INOSINE, XANTHOSINE, DEOXY-INOSINE, DEOXYGUANOSINE, INOSINE-2',3'-(ACYCLIC)-DIALCOHOL OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, HEMOPOIESIS-STIMULATING PHARMACEUTICAL COMPOSITION, METHOD OF TREATMENT OF CYTOPENIA

organic chemistry, heterocyclic compounds, pharmacy. SUBSTANCE: invention relates to the novel acyl derivatives of guanosine of the formula (I) , inosine of the formula (II) , xanthosine of the formula (III) , deoxyinosine of the formula (IV) , deoxyguanosine of the formula (V) , inosine-2', 3&...

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Hauptverfasser: DZHEJMS CHARL'Z BATLER, REJD UORREN FON BORSTEL, MAJKL KEVIN BEHMAT, BREHDLI MARK KHILTBREHND
Format: Patent
Sprache:eng
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Zusammenfassung:organic chemistry, heterocyclic compounds, pharmacy. SUBSTANCE: invention relates to the novel acyl derivatives of guanosine of the formula (I) , inosine of the formula (II) , xanthosine of the formula (III) , deoxyinosine of the formula (IV) , deoxyguanosine of the formula (V) , inosine-2', 3'-(acyclic)-dialcohol of the formula (VI) or their pharmaceutically acceptable salts. Values of radicals RA,RB,RC,RD, Y, Q and Z are given in corresponding points of the invention claim. Invention describes a pharmaceutical composition stimulating hemopoiesis and containing derivatives of guanosine or inosine or their salts as an active agent. Invention proposes also method of treatment of animals with cytopenia by administration of indicated compounds in effective doses. Invention can be used in medicinal practice and therapy in hemopoiesis disorders. EFFECT: compounds indicated above, valuable medicinal properties. 17 cl, 68 dwg, 53 ex