DERIVATIVES OF PHENYLCYCLOHEXYLCARBOXYLIC ACID AMIDE, MIXTURE OF THEIR OR SEPARATE ISOMERS AND THEIR SALTS, PHARMACEUTICAL COMPOSITION WITH ANTIARTERIOSCLEROTIC AND ANTIRESTENOSIS ACTIVITY
organic chemistry, pharmacy. SUBSTANCE: invention relates to derivatives of phenylcyclohexylcarboxylic acid amide of the general formula (I) where D is the group -CH- or nitrogen atom; R1 is phenyl, cycloalkyl with 3-6 carbon atoms, direct or branched alkyl with 1-5 carbon atoms; R2 is direct or bra...
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| creator | SHTEFAN VOL'FAJL' MATTIAS MJULLER-GLIMANN SHTEFAN LOMER ETSKAN JALKINOGLU UL'RIKH MJULLER DIRK DENTSER MARTIN BOJK RUDI GRJUTTSMANN ZIGFRID TSAJSS ANKE DOMDAJ-BETTE KRISTOF GERDES DZHEJMS EHL'TING |
| description | organic chemistry, pharmacy. SUBSTANCE: invention relates to derivatives of phenylcyclohexylcarboxylic acid amide of the general formula (I) where D is the group -CH- or nitrogen atom; R1 is phenyl, cycloalkyl with 3-6 carbon atoms, direct or branched alkyl with 1-5 carbon atoms; R2 is direct or branched alkoxycarbonyl with 1-5 carbon atoms or residue of the formula -CO-NH2 or -CH2--OH, mixture of their isomers or separate isomers and their salts. Invention relates to also pharmaceutical composition based on compounds indicated above showing antiarteriosclerotic and antirestenosis activities. EFFECT: valuable medicinal properties of compounds. 5 cl, 3 tbl, 8 ex |
| format | Patent |
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SUBSTANCE: invention relates to derivatives of phenylcyclohexylcarboxylic acid amide of the general formula (I) where D is the group -CH- or nitrogen atom; R1 is phenyl, cycloalkyl with 3-6 carbon atoms, direct or branched alkyl with 1-5 carbon atoms; R2 is direct or branched alkoxycarbonyl with 1-5 carbon atoms or residue of the formula -CO-NH2 or -CH2--OH, mixture of their isomers or separate isomers and their salts. Invention relates to also pharmaceutical composition based on compounds indicated above showing antiarteriosclerotic and antirestenosis activities. 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SUBSTANCE: invention relates to derivatives of phenylcyclohexylcarboxylic acid amide of the general formula (I) where D is the group -CH- or nitrogen atom; R1 is phenyl, cycloalkyl with 3-6 carbon atoms, direct or branched alkyl with 1-5 carbon atoms; R2 is direct or branched alkoxycarbonyl with 1-5 carbon atoms or residue of the formula -CO-NH2 or -CH2--OH, mixture of their isomers or separate isomers and their salts. Invention relates to also pharmaceutical composition based on compounds indicated above showing antiarteriosclerotic and antirestenosis activities. 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SUBSTANCE: invention relates to derivatives of phenylcyclohexylcarboxylic acid amide of the general formula (I) where D is the group -CH- or nitrogen atom; R1 is phenyl, cycloalkyl with 3-6 carbon atoms, direct or branched alkyl with 1-5 carbon atoms; R2 is direct or branched alkoxycarbonyl with 1-5 carbon atoms or residue of the formula -CO-NH2 or -CH2--OH, mixture of their isomers or separate isomers and their salts. Invention relates to also pharmaceutical composition based on compounds indicated above showing antiarteriosclerotic and antirestenosis activities. EFFECT: valuable medicinal properties of compounds. 5 cl, 3 tbl, 8 ex</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | DERIVATIVES OF PHENYLCYCLOHEXYLCARBOXYLIC ACID AMIDE, MIXTURE OF THEIR OR SEPARATE ISOMERS AND THEIR SALTS, PHARMACEUTICAL COMPOSITION WITH ANTIARTERIOSCLEROTIC AND ANTIRESTENOSIS ACTIVITY |
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