STRAIN OF BACTERIUM VIBRIO CHOLERAE CHOLERAE 5 SEROVARA OGAVA AS PRODUCER OF ANTIBODY TO CHOLERAIC OGAVA SERUM

medicine, microbiology. SUBSTANCE: strain Vibrio cholerae cholerae 01KM 193 5 serovara Ogava is a producer of antibodies. Strain is used for preparing choleraic agglutinating Ogava serum. Strain shows good sequences of operon of gene determining synthesis of subunits A and B of choleragen. Strain sh...

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Hauptverfasser: BALAKHONOV S.V, MIKHAJLOVA V.A, BELOBORODOV JU.V, ANDREEVSKAJA N.M, KARETNIKOVA EH.S
Format: Patent
Sprache:eng
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Zusammenfassung:medicine, microbiology. SUBSTANCE: strain Vibrio cholerae cholerae 01KM 193 5 serovara Ogava is a producer of antibodies. Strain is used for preparing choleraic agglutinating Ogava serum. Strain shows good sequences of operon of gene determining synthesis of subunits A and B of choleragen. Strain shows high antigenic properties. In immunization of horses and rabbits with O-antigen the strain stimulates formation of specific antibodies in high titers. Invention can be used for laboratory diagnosis of cholera and for immunological and genetic investigations also. EFFECT: enhanced activity and specificity of choleraic Ogava serum. 2 ex