QUATERNARY AMMONIUM BASE TRIIODIDES AND THEIR WATER-SOLUBLE COMPOSITION
organic synthesis and biologically-active compounds. SUBSTANCE: invention provides novel quaternary ammonium base triiodides with formulas I-IV: , , , and , in which R1, R2, R3, R4, R8, R9 are hydrogen or C1-C6- alkyl; R7 is (n12 = 2-4), (n14 = 0-4 and n15 = 0-4), (n16 = 0-4 and n17 = 0-4), (n18 = 0...
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Format: | Patent |
Sprache: | eng |
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Zusammenfassung: | organic synthesis and biologically-active compounds. SUBSTANCE: invention provides novel quaternary ammonium base triiodides with formulas I-IV: , , , and , in which R1, R2, R3, R4, R8, R9 are hydrogen or C1-C6- alkyl; R7 is (n12 = 2-4), (n14 = 0-4 and n15 = 0-4), (n16 = 0-4 and n17 = 0-4), (n18 = 0-4, n19 = 0-4, R20 is hydrogen or C1-C6/ - alkyl), (n20 = 0-4, n21= 0-4 = 0-4, R21, R22 are hydrogen or C1-C6-alkyl, and X is I, I3); R10, R11, R12 are hydrogen, C1-C6-alkyl; n1, n2 are 3 or 4; and X is I, I3. Above defined compounds are useful for preparing water-soluble antimicrobial composition, in which ammonium triiodides constitute 1 to 40%, the rest being a surfactant. Compositions are administered orally or parenterally. EFFECT: enlarged resource of antimicrobial drugs. 2 cl, 2 tbl, 7 ex |
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