SULFONAMIDES AND PHARMACEUTICAL COMPOSITION

organic chemistry, pharmacy. SUBSTANCE: invention relates to the novel sulfonamides of the general formula (I): where R1-R8, A and B have values given in the invention claim. Claimed compounds are inhibitors of endothelin and can be used for treatment of patients with diseases associated with endoth...

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Bibliographische Detailangaben
Hauptverfasser:	MJULLER MARSEL, BURRI KASPAR, KASSAL' ZHAN-MARI, KHIRT ZHORZH, NAJDKHARD VERNER, LEFFLER BERND-MIKHAEHL, BROJ FOL'KER, RAMUZ KHENRI, KLOZEL' MARTIN
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	organic chemistry, pharmacy. SUBSTANCE: invention relates to the novel sulfonamides of the general formula (I): where R1-R8, A and B have values given in the invention claim. Claimed compounds are inhibitors of endothelin and can be used for treatment of patients with diseases associated with endothelin activities, for example, hypertension and also to pharmaceutical compositions based on thereof. EFFECT: valuable curative properties of composition. 13 cl, 3 tbl, 77 ex