PREPARATION FOR PHOTODYNAMIC THERAPY

FIELD: medicine, oncology. SUBSTANCE: invention relates to preparations used for photodynamic therapy of patients with malignant neoplasms. Preparation for photodynamic therapy is phosphinemethyl derivatives of phthalocyanine of the general formula: PcM[CH2PO(OR)2]n where M is AlX, Zn, SnX2, SiX2, T...

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Hauptverfasser: LOSHCHENOV V.B, MEEROVICH G.A, JUZHAKOVA O.A, TORSHINA N.L, LUK'JANETS E.A, VOROZHTSOV G.N, LUZHKOV JU.M, KOGAN E.A
Format: Patent
Sprache:eng
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Zusammenfassung:FIELD: medicine, oncology. SUBSTANCE: invention relates to preparations used for photodynamic therapy of patients with malignant neoplasms. Preparation for photodynamic therapy is phosphinemethyl derivatives of phthalocyanine of the general formula: PcM[CH2PO(OR)2]n where M is AlX, Zn, SnX2, SiX2, TiO; X is OH, OP(O)R(OR), Br or other halogen; R is H, C2H5 or other alkyl; n > 4 for Zn; n >= 2 for tri- and tetravalent metals. Preparation exerts the greater deep effect on tissues. EFFECT: enhanced effectiveness of preparation as compared with known ones. 16 ex