THROMBIN INHIBITORS OF SELECTIVE ACTION AND PHARMACEUTICAL COMPOSITION BASED ON SAID

FIELD: organic chemistry, pharmacy. SUBSTANCE: invention describes selective inhibitors of thrombin of the following formula (I) R1,R6,R where values , X are given in p. 1 of the invention claim. These compounds can be used orally also. Invention describes also a pharmaceutical composition based on...

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Hauptverfasser: MI K'JUNG JUN, SANG SU KIM, JU SEUNG SHIN, JEONG SU OKH, SANG JEUL KHVANG, SEONG R'JUL KHVANG, JIDZHEONG, SEONG VON KHONG, JONG KHI LI, KU LI
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creator MI K'JUNG JUN
SANG SU KIM
JU SEUNG SHIN
JEONG SU OKH
SANG JEUL KHVANG
SEONG R'JUL KHVANG
JIDZHEONG
SEONG VON KHONG
JONG KHI LI
KU LI
description FIELD: organic chemistry, pharmacy. SUBSTANCE: invention describes selective inhibitors of thrombin of the following formula (I) R1,R6,R where values , X are given in p. 1 of the invention claim. These compounds can be used orally also. Invention describes also a pharmaceutical composition based on compounds of the formula (II) used for inhibition of thrombin activity. EFFECT: valuable pharmacological properties of compounds. 4 cl, 7 tbl, 58 ex
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title THROMBIN INHIBITORS OF SELECTIVE ACTION AND PHARMACEUTICAL COMPOSITION BASED ON SAID
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