THROMBIN INHIBITORS OF SELECTIVE ACTION AND PHARMACEUTICAL COMPOSITION BASED ON SAID

FIELD: organic chemistry, pharmacy. SUBSTANCE: invention describes selective inhibitors of thrombin of the following formula (I) R1,R6,R where values , X are given in p. 1 of the invention claim. These compounds can be used orally also. Invention describes also a pharmaceutical composition based on...

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Hauptverfasser:	MI K'JUNG JUN, SANG SU KIM, JU SEUNG SHIN, JEONG SU OKH, SANG JEUL KHVANG, SEONG R'JUL KHVANG, JIDZHEONG, SEONG VON KHONG, JONG KHI LI, KU LI
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	FIELD: organic chemistry, pharmacy. SUBSTANCE: invention describes selective inhibitors of thrombin of the following formula (I) R1,R6,R where values , X are given in p. 1 of the invention claim. These compounds can be used orally also. Invention describes also a pharmaceutical composition based on compounds of the formula (II) used for inhibition of thrombin activity. EFFECT: valuable pharmacological properties of compounds. 4 cl, 7 tbl, 58 ex