METHOD OF INDUSTRIAL PRODUCING POLYPEPTIDE SHOWING BIOLOGICAL ACTIVITY OF HUMAN LEUKOCYTE INTERFERON ALPHA-2

FIELD: biotechnology, polypeptides. SUBSTANCE: recombinant bacterial cells Pseudomonas species VG-84 are cultured on the nutrient medium containing glucose (25-60 g/l), streptomycin and tetracycline. Culturing is carried out under aeration conditions. Culturing can be performed at the batch feeding...

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Hauptverfasser: NAUMOVA N.V, PIKALOVA M.I, KOLOKOL'TSOV A.A, KHAJBULLINA I.I, ENIKEEVA R.V, DOMANOVA Z.M
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creator NAUMOVA N.V
PIKALOVA M.I
KOLOKOL'TSOV A.A
KHAJBULLINA I.I
ENIKEEVA R.V
DOMANOVA Z.M
description FIELD: biotechnology, polypeptides. SUBSTANCE: recombinant bacterial cells Pseudomonas species VG-84 are cultured on the nutrient medium containing glucose (25-60 g/l), streptomycin and tetracycline. Culturing is carried out under aeration conditions. Culturing can be performed at the batch feeding the nutrient medium containing glucose (80 g/l). Invention can be used for the industrial large-scale production of human recombinant interferon. EFFECT: increased yield of the human recombinant interferon alpha-2. 2 cl, 3 tbl, 3 dwg, 2 ex
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title METHOD OF INDUSTRIAL PRODUCING POLYPEPTIDE SHOWING BIOLOGICAL ACTIVITY OF HUMAN LEUKOCYTE INTERFERON ALPHA-2
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