METHOD OF INDUSTRIAL PRODUCING POLYPEPTIDE SHOWING BIOLOGICAL ACTIVITY OF HUMAN LEUKOCYTE INTERFERON ALPHA-2

FIELD: biotechnology, polypeptides. SUBSTANCE: recombinant bacterial cells Pseudomonas species VG-84 are cultured on the nutrient medium containing glucose (25-60 g/l), streptomycin and tetracycline. Culturing is carried out under aeration conditions. Culturing can be performed at the batch feeding...

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Bibliographische Detailangaben
Hauptverfasser:	NAUMOVA N.V, PIKALOVA M.I, KOLOKOL'TSOV A.A, KHAJBULLINA I.I, ENIKEEVA R.V, DOMANOVA Z.M
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	FIELD: biotechnology, polypeptides. SUBSTANCE: recombinant bacterial cells Pseudomonas species VG-84 are cultured on the nutrient medium containing glucose (25-60 g/l), streptomycin and tetracycline. Culturing is carried out under aeration conditions. Culturing can be performed at the batch feeding the nutrient medium containing glucose (80 g/l). Invention can be used for the industrial large-scale production of human recombinant interferon. EFFECT: increased yield of the human recombinant interferon alpha-2. 2 cl, 3 tbl, 3 dwg, 2 ex