METHOD OF PROGNOSTICATION OF DEVELOPMENT OF CHRONIC COURSE OF MITE-BORNE SYSTEMIC BORRELIOSIS IN CHILDREN

FIELD: medicine, particularly, methods of prognostication of development of chronic forms of mite-borne systemic borreliosis in children; applicable in clinical practice. SUBSTANCE: method consists in that determined simultaneously in patient's blood serum in common system of reactions is conce...

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Hauptverfasser: SOROKINA M.N, MURINA E.A, AKSENOV O.A, IVANOVA G.P
Format: Patent
Sprache:eng
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Zusammenfassung:FIELD: medicine, particularly, methods of prognostication of development of chronic forms of mite-borne systemic borreliosis in children; applicable in clinical practice. SUBSTANCE: method consists in that determined simultaneously in patient's blood serum in common system of reactions is concentration of antibodies to borrelias, level of specific immune complexes and non-specific immune complexes containing no complement. If, at the end of acute period, antibodies amount to less than 0.20 unit, with non complement-containing specific immune complexes, no concentration of immune complexes containing no complement more than 40 units, development of chronic form of mite-borne systemic borreliosis is prognosticated. Application of claimed method of prognostication resulted in improvement of disease termination and reduced transition in chronic forms from 20-18% in 1995-96 down to 11% in 1997. EFFECT: improved terminations of disease and prevented transition from acute course of disease to chronic one. 1 cl