4-HYDROXYPYRAN-2-ONES, CYCLOOCTYL- OR BENZOPYRAN-2-ONES, 4-HYDROXY-2H-PYRAN-2-ONES AND HYDROXYCYCLOOCTANEPYRAN-2- ONES

4-HYDROXYPYRAN-2-ONES, CYCLOOCTYL- OR BENZOPYRAN-2-ONES, 4-HYDROXY-2H-PYRAN-2-ONES AND HYDROXYCYCLOOCTANEPYRAN-2- ONES

FIELD: medicine. SUBSTANCE: hydroxypyran-2- ones of formula I R1 wherein R2 is H; C3-5 is (CH2)2 alkyl, phenyl- -SO2NH-(CH2)2, het--(CH2)2, cyclopropyl--(CH2)2, fluorophenyl--SO2NH-, het-(CH2)2- phenyl, trifluoromethyl-R1 and R2, or R3 together form double bond; R4 is fragment of formula (A), -SO2NH...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: RUBEN A.TOMMASI, RONAL'D B.GAMMILL, DZHOZEF VAL'TER STROBACH, STIVEN RONAL'D TERNER, KHARVEJ IRVING SKALNIK, SAVIT TAISRIVONGS, DZHORDZH P.LJUK, DZHOEHL MORRIS, TEREZA M.SHVARTS, POL ADRIAN ARISTOFF, DEHVID DZHON ANDERSON, POL D.DZHONSON, KAREN RENE ROMINES, GORDON L.BANDI, LUIS L.SKALETSKI
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:FIELD: medicine. SUBSTANCE: hydroxypyran-2- ones of formula I R1 wherein R2 is H; C3-5 is (CH2)2 alkyl, phenyl- -SO2NH-(CH2)2, het--(CH2)2, cyclopropyl--(CH2)2, fluorophenyl--SO2NH-, het-(CH2)2- phenyl, trifluoromethyl-R1 and R2, or R3 together form double bond; R4 is fragment of formula (A), -SO2NH- is phenyl, het, cyclopropyl, bromine; azido, het- and derivatives thereof are useful for suppressing retrovirus in human cells infected by said retrovirus. EFFECT: improved properties of title compounds. 40 cl, 119 dwg, 380 ex, 3 tbl