IBUPROFEN-CONTAINING PHARMACEUTICAL COMPOSITION, PHARMACEUTICAL PREPARATION ON SAID AND METHOD OF ITS PREPARING

FIELD: pharmacy. SUBSTANCE: invention relates to a new pharmaceutical composition designated for preparing powders or carbonated tablets containing ibuprofen or one of its pharmaceutically acceptable salts as an active component. Composition has: ibuprofen or one of its pharmaceutically acceptable s...

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Bibliographische Detailangaben
Hauptverfasser: NIKOL' BRJU-MAN'EZ, ZHAN-FRANSUA KORDOL'JANI, ZHERAR TOVEHN, ZHEAN-IV DRUEHN
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:FIELD: pharmacy. SUBSTANCE: invention relates to a new pharmaceutical composition designated for preparing powders or carbonated tablets containing ibuprofen or one of its pharmaceutically acceptable salts as an active component. Composition has: ibuprofen or one of its pharmaceutically acceptable salts taken at effective amount, pharmaceutically acceptable carbonating system containing at least a single alkaline carbonate and at least a single organic acid taken at amount that is sufficient to obtain pH below about 8, at least a single pharmaceutically acceptable antioxidant taken at amount that is sufficient for ibuprofen stabilization. EFFECT: improved stability of powder or tablet composition. 16 cl, 4 tbl, 2 ex