THIOFORMAMIDE DERIVATIVES OR THEIR PHARMACOLOGICALLY ACCEPTABLE SALTS
FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to derivatives of thioformamide of the general formula (I) where Y - a group of the formula -C(O)-, -CH(OH)-, =N-O-Ph, O=C(Ph)-O ; Z means ; A means substituted or nonsubstituted imidazopyridyl; R1, R2, R and R - hydrogen or lower alky...
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| creator | KEJDZI ISIBASI NOBUJUKI MORI KHITOSI OJNUMA KHIDEJUKI ADATI KHIDETO OKHARA KHIROSI KATO NORIO MINAMI TOSIAKI OGAVA KOKHTARO KODAMA FUMIKHIRO OZAKI TAKASI KHASEGAVA JASUKHIRO KABASAVA |
| description | FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to derivatives of thioformamide of the general formula (I) where Y - a group of the formula -C(O)-, -CH(OH)-, =N-O-Ph, O=C(Ph)-O ; Z means ; A means substituted or nonsubstituted imidazopyridyl; R1, R2, R and R - hydrogen or lower alkyl, or their pharmaceutically acceptable salts exhibiting high hypotensive properties. EFFECT: improved method of synthesis, enhanced pharmacological activity of compounds. 6 cl, 24 ex, 1 tbl |
| format | Patent |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | THIOFORMAMIDE DERIVATIVES OR THEIR PHARMACOLOGICALLY ACCEPTABLE SALTS |
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