PREPARATION FOR TREATMENT OF CONNECTIVE TISSUE PATHOLOGICAL STATE

FIELD: medicine. SUBSTANCE: preparation has conjugate of an enzyme hyaluronidase with high-molecular synthetic carrier polyoxydonium (molecular mass is 40 000-100 000 Da). Preparation has molecular links (n) in the amount 300-700, alkylated links in the amount (0.2-0.4) x n, oxidizing links in the a...

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Hauptverfasser: IVANOVA AL'BERTA SERGEEVNA, KHAITOV RAKHIM MUSAEVICH, NEKRASOV ARKADIJ VASIL'EVICH, ATAULLAKHANOV RAVSHAN INOJATOVICH, PUCHKOVA NATAL'JA GRIGOR'EVNA, PETROV REHM VIKTOROVICH
Format: Patent
Sprache:eng ; rus
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Zusammenfassung:FIELD: medicine. SUBSTANCE: preparation has conjugate of an enzyme hyaluronidase with high-molecular synthetic carrier polyoxydonium (molecular mass is 40 000-100 000 Da). Preparation has molecular links (n) in the amount 300-700, alkylated links in the amount (0.2-0.4) x n, oxidizing links in the amount (0.4-0.8) x n at ratio enzyme : carrier = 1:(1-5). Specific activity of enzyme hyaluronidase is 1 000-2 500 IU/mg that can be prepared from cattle testicles. EFFECT: enhanced effectiveness of preparation. 2 tblf