DERIVATIVES OF $$$-(TERTIARY AMINOMETHYL)-BENZENEMETHANOL AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF

FIELD: organic chemistry. SUBSTANCE: invention proposes new compounds of the general formula (I) where a substituent $$$ is taken from alkyl, alkoxy-, alkenyloxy-, arylalkoxy-, alkylthio- and alkenylthio-groups; substituent $$$ is taken from halogen atom, hydroxy-group, alkyl, alkoxy-, alkenyloxy-,...

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Hauptverfasser: NIL'S-EHRIK VILLMAN, GUSTAV LENNART PERSSON, LENNART GUSTAV NORD, BENGT KRISTER KHANS SHEGREN
Format: Patent
Sprache:eng
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Zusammenfassung:FIELD: organic chemistry. SUBSTANCE: invention proposes new compounds of the general formula (I) where a substituent $$$ is taken from alkyl, alkoxy-, alkenyloxy-, arylalkoxy-, alkylthio- and alkenylthio-groups; substituent $$$ is taken from halogen atom, hydroxy-group, alkyl, alkoxy-, alkenyloxy-, alkylthio-, alkenylthio-, alkylamino-group, trifluoromethyl, cyano-, nitro-, alkylsulfinyl, alkylsulfonyl and acyl groups; substituents $$$ and $$$ independently each of other mean alkyl or alkenyl or together form heterocyclic system with nitrogen atom optionally containing one or more additional heteroatoms. Invention relates to pharmaceutically acceptable salts and the use of these compounds as therapeutic agents, in part, for control of diuresis and for preparing drug controlling diuresis, pharmaceutical compositions containing these compounds and methods of synthesis of new compounds also. EFFECT: improved method of synthesis. 5 cl, 1 tbl