STRAIN AMYCOLATOPSIS ORIENTALIS SUBSPECIES EREMOMYCINI VKPM-S892 - A PRODUCER OF ANTIBIOTIC EREMOMYCIN AND A METHOD OF ANTIBIOTIC EREMOMYCIN PRODUCING

FIELD: biotechnology, antibiotics. SUBSTANCE: after termination of biosynthesis antibiotic is sorbed on carboxyl cation-exchange resin KB-2 in salt form and eluted with ammonia solution. Then eluate is neutralized, desalted and passed through sorbent ÅÆöØ.. Eremomycin is eluted from sorbent with wat...

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Hauptverfasser: SABUROVA T.P, LOMAKINA N.N, SVESHNIKOVA M.A, FILIPPOS'JANTS S.T, MAKAROVA M.O, LAJKO A.V, FEDOROVA G.B, BERDNIKOVA T.F, ARKHANGEL'SKAJA N.M, SHAPOVALOVA S.P, POGOZHEVA V.V, PREOBRAZHENSKAJA T.P, KATRUKHA G.S, GLADKIKH E.G, BRAZHNIKOVA M.G, GOLOVA T.P, SHEPELEVTSEVA N.G, LAPCHINSKAJA O.A, TOLSTYKH I.V
Format: Patent
Sprache:eng ; rus
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Zusammenfassung:FIELD: biotechnology, antibiotics. SUBSTANCE: after termination of biosynthesis antibiotic is sorbed on carboxyl cation-exchange resin KB-2 in salt form and eluted with ammonia solution. Then eluate is neutralized, desalted and passed through sorbent ÅÆöØ.. Eremomycin is eluted from sorbent with water, concentrated under vacuum up to content 120-140 mg/ml and crystallized as sulfate. EFFECT: strain indicated above, improved method of production. 2 cl, 2 tbls