METHOD FOR STEREOSPECIFIC HYDROLYSIS OF PIPERIDINEDIONE DERIVATIVES

METHOD FOR STEREOSPECIFIC HYDROLYSIS OF PIPERIDINEDIONE DERIVATIVES

FIELD: biotechnology, namely production compounds having antidepressant activity. SUBSTANCE: mixture of (+) and (-) isomers of piperidinedione derivatives is affected by stereospecific hydrolysis which takes place with the help of carboxyl esterase ferment in mixture of aqueous and organic solvents....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: LOSON UILL'JAM PAUEHLL, ALAN DEHVID KURZONS, ALAN MARTIN KI
Format: Patent
Sprache:eng
Schlagworte:
BEER
BIOCHEMISTRY
CHEMISTRY
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
HETEROCYCLIC COMPOUNDS
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
SPIRITS
VINEGAR
WINE
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Beschreibung
Zusammenfassung:FIELD: biotechnology, namely production compounds having antidepressant activity. SUBSTANCE: mixture of (+) and (-) isomers of piperidinedione derivatives is affected by stereospecific hydrolysis which takes place with the help of carboxyl esterase ferment in mixture of aqueous and organic solvents. Products of hydrolysis are then separated. EFFECT: improved efficiency of the method. 3 clc