IMIDAZOLE DERIVATIVES, METHOD OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION DECREASING BLOOD PRESSURE
FIELD: organic chemistry. SUBSTANCE: product: imidazole derivatives of the formula: $$$ where $$$ - $$$-alkyl; $$$ - halogen, $$$-alkylthio, $$$-alkoxy; $$$ - CHO, COOH, $$$-alkyl; $$$ means group $$$; $$$ and $$$ are different and mean hydrogen, $$$-alkyl that can contain different substituents, or...
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Sprache: | eng |
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Zusammenfassung: | FIELD: organic chemistry. SUBSTANCE: product: imidazole derivatives of the formula: $$$ where $$$ - $$$-alkyl; $$$ - halogen, $$$-alkylthio, $$$-alkoxy; $$$ - CHO, COOH, $$$-alkyl; $$$ means group $$$; $$$ and $$$ are different and mean hydrogen, $$$-alkyl that can contain different substituents, or $$$ and $$$ together with nitrogen atom form $$$-heteroaryl ring and others. The synthesized compounds were used in medicine as hypotensive agents. EFFECT: improved method of synthesis. 9 cl, 8 tbl |
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