ISOINDOLONE DERIVATIVES OR THEIR SALTS WITH ACIDS AS INTERMEDIATE COMPOUNDS FOR SYNTHESIS OF BIOLOGICALLY ACTIVE COMPOUNDS - PERHYDROISOINDOLONES
FIELD: organic chemistry. SUBSTANCE: products: derivatives of isoindolone of the formula (I) $$$ where R means hydrogen atoms or form bond together; R' means hydrogen atom, allyl or radical of the formula -C-$$$ where $$$ and $$$ means hydrogen or phenyl possibly substituted with halogen, alkyl...
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creator | MARI-KRISTIN DJUBREK ZHAN-FRANSUA PEJRONEL MISHEL' TABAR KLOD MUTONN'E ALAN TRJUSHON |
description | FIELD: organic chemistry. SUBSTANCE: products: derivatives of isoindolone of the formula (I) $$$ where R means hydrogen atoms or form bond together; R' means hydrogen atom, allyl or radical of the formula -C-$$$ where $$$ and $$$ means hydrogen or phenyl possibly substituted with halogen, alkyl, alkylhydroxy- or nitro-group; $$$ has values $$$ and $$$ or means alkyl or alkylhydroxyalkyl being at least one of $$$ and $$$ means free or substituted phenyl; radicals R'' are similar and mean phenyl radicals as (3aR, 7aR) or as a mixture of forms (3aRS, 7aRS), or their salts with acids. Reagent 1: compound of the formula R'-$$$. Reagent 2: derivative of cyclohexenone of the formula (II) $$$ where R, R' and R'' have above indicated values. Reaction conditions: in the presence of catalytic amount of oxygen in organic solvent. EFFECT: improved method of synthesis. 3 tbl |
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SUBSTANCE: products: derivatives of isoindolone of the formula (I) $$$ where R means hydrogen atoms or form bond together; R' means hydrogen atom, allyl or radical of the formula -C-$$$ where $$$ and $$$ means hydrogen or phenyl possibly substituted with halogen, alkyl, alkylhydroxy- or nitro-group; $$$ has values $$$ and $$$ or means alkyl or alkylhydroxyalkyl being at least one of $$$ and $$$ means free or substituted phenyl; radicals R'' are similar and mean phenyl radicals as (3aR, 7aR) or as a mixture of forms (3aRS, 7aRS), or their salts with acids. Reagent 1: compound of the formula R'-$$$. Reagent 2: derivative of cyclohexenone of the formula (II) $$$ where R, R' and R'' have above indicated values. Reaction conditions: in the presence of catalytic amount of oxygen in organic solvent. EFFECT: improved method of synthesis. 3 tbl</description><edition>6</edition><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1998</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19980210&DB=EPODOC&CC=RU&NR=2104269C1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76318</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19980210&DB=EPODOC&CC=RU&NR=2104269C1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>MARI-KRISTIN DJUBREK</creatorcontrib><creatorcontrib>ZHAN-FRANSUA PEJRONEL</creatorcontrib><creatorcontrib>MISHEL' TABAR</creatorcontrib><creatorcontrib>KLOD MUTONN'E</creatorcontrib><creatorcontrib>ALAN TRJUSHON</creatorcontrib><title>ISOINDOLONE DERIVATIVES OR THEIR SALTS WITH ACIDS AS INTERMEDIATE COMPOUNDS FOR SYNTHESIS OF BIOLOGICALLY ACTIVE COMPOUNDS - PERHYDROISOINDOLONES</title><description>FIELD: organic chemistry. SUBSTANCE: products: derivatives of isoindolone of the formula (I) $$$ where R means hydrogen atoms or form bond together; R' means hydrogen atom, allyl or radical of the formula -C-$$$ where $$$ and $$$ means hydrogen or phenyl possibly substituted with halogen, alkyl, alkylhydroxy- or nitro-group; $$$ has values $$$ and $$$ or means alkyl or alkylhydroxyalkyl being at least one of $$$ and $$$ means free or substituted phenyl; radicals R'' are similar and mean phenyl radicals as (3aR, 7aR) or as a mixture of forms (3aRS, 7aRS), or their salts with acids. Reagent 1: compound of the formula R'-$$$. Reagent 2: derivative of cyclohexenone of the formula (II) $$$ where R, R' and R'' have above indicated values. Reaction conditions: in the presence of catalytic amount of oxygen in organic solvent. 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SUBSTANCE: products: derivatives of isoindolone of the formula (I) $$$ where R means hydrogen atoms or form bond together; R' means hydrogen atom, allyl or radical of the formula -C-$$$ where $$$ and $$$ means hydrogen or phenyl possibly substituted with halogen, alkyl, alkylhydroxy- or nitro-group; $$$ has values $$$ and $$$ or means alkyl or alkylhydroxyalkyl being at least one of $$$ and $$$ means free or substituted phenyl; radicals R'' are similar and mean phenyl radicals as (3aR, 7aR) or as a mixture of forms (3aRS, 7aRS), or their salts with acids. Reagent 1: compound of the formula R'-$$$. Reagent 2: derivative of cyclohexenone of the formula (II) $$$ where R, R' and R'' have above indicated values. Reaction conditions: in the presence of catalytic amount of oxygen in organic solvent. EFFECT: improved method of synthesis. 3 tbl</abstract><edition>6</edition><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | ISOINDOLONE DERIVATIVES OR THEIR SALTS WITH ACIDS AS INTERMEDIATE COMPOUNDS FOR SYNTHESIS OF BIOLOGICALLY ACTIVE COMPOUNDS - PERHYDROISOINDOLONES |
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