ISOINDOLONE DERIVATIVES OR THEIR SALTS WITH ACIDS AS INTERMEDIATE COMPOUNDS FOR SYNTHESIS OF BIOLOGICALLY ACTIVE COMPOUNDS - PERHYDROISOINDOLONES

FIELD: organic chemistry. SUBSTANCE: products: derivatives of isoindolone of the formula (I) $$$ where R means hydrogen atoms or form bond together; R' means hydrogen atom, allyl or radical of the formula -C-$$$ where $$$ and $$$ means hydrogen or phenyl possibly substituted with halogen, alkyl, alkylhydroxy- or nitro-group; $$$ has values $$$ and $$$ or means alkyl or alkylhydroxyalkyl being at least one of $$$ and $$$ means free or substituted phenyl; radicals R'' are similar and mean phenyl radicals as (3aR, 7aR) or as a mixture of forms (3aRS, 7aRS), or their salts with acids. Reagent 1: compound of the formula R'-$$$. Reagent 2: derivative of cyclohexenone of the formula (II) $$$ where R, R' and R'' have above indicated values. Reaction conditions: in the presence of catalytic amount of oxygen in organic solvent. EFFECT: improved method of synthesis. 3 tbl