NERVOUS-MUSCLE BLOCKATOR, ITS SYNTHESIS, PHARMACEUTICAL COMPOSITION AND METHOD OF PROVIDING NERVOUS-MUSCLE BLOCKADE IN ANIMALS

FIELD: medicine. SUBSTANCE: product: physiologically acceptable 1R-cis, 1'R-cis-2,2'-(3,11-dioxo-4,10-dioxatridecylene)-bis- -1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-veratryl isoquinoline salt free of other geometric and optical isomers, and composition stimulating nervous-muscle block...

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Hauptverfasser: DEREK EHNTONI KHILL, DZHEFFRI LLOJD TERNER
Format: Patent
Sprache:eng
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Zusammenfassung:FIELD: medicine. SUBSTANCE: product: physiologically acceptable 1R-cis, 1'R-cis-2,2'-(3,11-dioxo-4,10-dioxatridecylene)-bis- -1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-veratryl isoquinoline salt free of other geometric and optical isomers, and composition stimulating nervous-muscle blockade based on thereof. 1R-cis, 1'R-cis-isomer shows preferable combination of pharmacological properties and less harmful effect on autonomic nervous system as compared with the known mixture of geometric and optical isomers. EFFECT: improved property, enhanced effectiveness. 11 cl, 1 tbl