ISOBUTYL SUBSTITUTED AMIDES OF METHANE SULFONYLQUINOLYL METHOXYPHENYLCYCLOALKYL ACETIC ACID OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS

ISOBUTYL SUBSTITUTED AMIDES OF METHANE SULFONYLQUINOLYL METHOXYPHENYLCYCLOALKYL ACETIC ACID OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS

FIELD: organic chemistry; pharmacology. SUBSTANCE: isobutyl substituted amides of methane sulfonylquinolyl methoxyphenylcycloalkyl acetic acid having formula where R is cyclohexyl for racemates and enantiomers, or R is also cycloheptyl for enantiomers has high pharmalogical activity. Said novel comp...

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Hauptverfasser: ARMIN KHATTSEL'MANN, ZIGFRID RADDATTS, KLAUS-KHEL'MUT MORS, ROMANIS FRUKHTMANN, MIKHAEHL' MATTSKE, RAJNER MJULLER-PEDDINGKHAUZ
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:FIELD: organic chemistry; pharmacology. SUBSTANCE: isobutyl substituted amides of methane sulfonylquinolyl methoxyphenylcycloalkyl acetic acid having formula where R is cyclohexyl for racemates and enantiomers, or R is also cycloheptyl for enantiomers has high pharmalogical activity. Said novel compounds are inhibitors of lipoxygenase. EFFECT: improved quality of desired product. 2 tbl