8-SUBSTITUTED-2-AMINOTETRALINE DERIVATIVES AND METHODS OF PREPARATION THEREOF

8-SUBSTITUTED-2-AMINOTETRALINE DERIVATIVES AND METHODS OF PREPARATION THEREOF

A compound of the formula Z is hydrogen or halogen, Q is COR or 5- or 6-membered aryl which may contain 1 or 2 heteroatoms selected from N, O or S and may be substituted or fused wherein R is hydrogen or C1-methyl (cis-configuration), R is C1-C6 alkyl or an aromatic ring which may contain heteroatom...

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Bibliographische Detailangaben
Hauptverfasser: ULI ALF KHAKSELL, KHONG IU, NILS-ERIK ANDEN, KARL ERK VALLGARDA, EVA SHARLOTTA MELLIN, EVA MARIE PERSSON, IE LIU, ANNA LENA MARIYA BERK, SVEN-ERIK KHILLVER, BERIT KRISTINA ELIZABET BAKLUND KHEK
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:A compound of the formula Z is hydrogen or halogen, Q is COR or 5- or 6-membered aryl which may contain 1 or 2 heteroatoms selected from N, O or S and may be substituted or fused wherein R is hydrogen or C1-methyl (cis-configuration), R is C1-C6 alkyl or an aromatic ring which may contain heteroatoms selected from O and S and may be substituted or fused to an optionally substituted benzene ring, R is hydrogen or C1-C6 alkyl and R may be different groups defined in claim 1, and enantiomers/salts thereof, processes for preparation of said compounds, pharmaceutical preparations containing said compounds, use of and method of treatment of disorders in CNS by using said compounds.