(4-AMINO-2,6-DIMETHYLPHENYLSULFONYL) NITROMETHANE, (4- ACETAMIDO-2,6-DIMETHYLPHENYLSULFONYL) NITROMETHANE AND PHARMACEUTICAL COMPOSITION HAVING PROPERTIES OF ALDOSOREDUCTASE ENZYME INHIBITOR

The invention discloses a novel aminophenylsulphone derivative (and its salts) which is an inhibitor of the enzyme aldose reductase, pharmaceutical compositions containing the novel derivative, and processes for its manufacture. The invention also discloses certain novel N-acyl derivatives of the am...

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Hauptverfasser:	LINDA SLETER, DEVID ROBERT BRITTEJN, ENTONI LOREN KUPER, DZHON PRESTON, STIVEN POL BRAUN, DZHETRO LORENS LONGRIDZH, DZHEFFRI DZHEJMS MORRIS
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention discloses a novel aminophenylsulphone derivative (and its salts) which is an inhibitor of the enzyme aldose reductase, pharmaceutical compositions containing the novel derivative, and processes for its manufacture. The invention also discloses certain novel N-acyl derivatives of the aminophenylsulphone derivative, which are useful in the production of the latter derivative.