4-CHLORO-3-SULFAMOYLBENZOIC ACID HYDRAZIDES SHOWING SALIDIURETIC AND DIURETIC ACTIVITIES

4-CHLORO-3-SULFAMOYLBENZOIC ACID HYDRAZIDES SHOWING SALIDIURETIC AND DIURETIC ACTIVITIES

The novel compounds according to the invention correspond to the general formula I in which R represents hydrogen, a trifluoromethyl or carboxyl group, an alkoxycarbonyl group having 2-5 carbon atoms, a cyano, benzoyl or sulphamoyl group or an alkylsulphonyl group having 1-4 carbon atoms, R represen...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: LASLO KHARSHING, VERA GERGELI, DERD SHIMON, ERZHEBET MOLNAR, ENDRE PALOSHI, KATALIN MARMAROSH, IDA SVOBODA, DEZHE KORBONITSH, SHANDOR VIRAG
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The novel compounds according to the invention correspond to the general formula I in which R represents hydrogen, a trifluoromethyl or carboxyl group, an alkoxycarbonyl group having 2-5 carbon atoms, a cyano, benzoyl or sulphamoyl group or an alkylsulphonyl group having 1-4 carbon atoms, R represents hydrogen, an alkylthio or alkylsulphonyl group each having 1-4 carbon atoms, a straight or branched alkyl group having 1-4 carbon atoms, or a benzylthio, benzylsulphonyl, phenyl, hydroxyl or thiol group and R represents hydrogen or chlorine. The novel compounds act as diuretics and saluretics and have a hypotensive action.