CRYSTALLINE MONOHYDRATE COMPLEX OF 1-CYANO-2-(4-CYCLOPROPYL-BENZYL)-4-(BETA-D-GLUCOPYRANOS-1-YL)-BENZENE AND L-PROLINE IN CRYSTAL WATER (1:1:1), METHODS FOR ITS PREPARATION AND ITS USE AS AN SGLT INHIBITOR

The invention relates to a mixture of crystalline forms comprising a crystalline monohydrate complex of 1-cyano-2-(4-cyclopropyl-benzyl)-4-(β-D-glucopyranos-1-yl)-benzene (compound A) and L-Proline in admixture with another form or forms of compound A.

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Hauptverfasser:	HIMMELSBACH, FRANK, ECKHARDT, MATTHIAS, BUTZ, TANJA, MARIA, MARTIN, HANS-JUERGEN
Format:	Patent
Sprache:	eng ; srp
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator	HIMMELSBACH, FRANK ECKHARDT, MATTHIAS BUTZ, TANJA, MARIA MARTIN, HANS-JUERGEN
description	The invention relates to a mixture of crystalline forms comprising a crystalline monohydrate complex of 1-cyano-2-(4-cyclopropyl-benzyl)-4-(β-D-glucopyranos-1-yl)-benzene (compound A) and L-Proline in admixture with another form or forms of compound A.
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subjects	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title	CRYSTALLINE MONOHYDRATE COMPLEX OF 1-CYANO-2-(4-CYCLOPROPYL-BENZYL)-4-(BETA-D-GLUCOPYRANOS-1-YL)-BENZENE AND L-PROLINE IN CRYSTAL WATER (1:1:1), METHODS FOR ITS PREPARATION AND ITS USE AS AN SGLT INHIBITOR
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