CRYSTALLINE MONOHYDRATE COMPLEX OF 1-CYANO-2-(4-CYCLOPROPYL-BENZYL)-4-(BETA-D-GLUCOPYRANOS-1-YL)-BENZENE AND L-PROLINE IN CRYSTAL WATER (1:1:1), METHODS FOR ITS PREPARATION AND ITS USE AS AN SGLT INHIBITOR

CRYSTALLINE MONOHYDRATE COMPLEX OF 1-CYANO-2-(4-CYCLOPROPYL-BENZYL)-4-(BETA-D-GLUCOPYRANOS-1-YL)-BENZENE AND L-PROLINE IN CRYSTAL WATER (1:1:1), METHODS FOR ITS PREPARATION AND ITS USE AS AN SGLT INHIBITOR

The invention relates to a mixture of crystalline forms comprising a crystalline monohydrate complex of 1-cyano-2-(4-cyclopropyl-benzyl)-4-(β-D-glucopyranos-1-yl)-benzene (compound A) and L-Proline in admixture with another form or forms of compound A.

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Bibliographische Detailangaben
Hauptverfasser: HIMMELSBACH, FRANK, ECKHARDT, MATTHIAS, BUTZ, TANJA, MARIA, MARTIN, HANS-JUERGEN
Format: Patent
Sprache:eng ; srp
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The invention relates to a mixture of crystalline forms comprising a crystalline monohydrate complex of 1-cyano-2-(4-cyclopropyl-benzyl)-4-(β-D-glucopyranos-1-yl)-benzene (compound A) and L-Proline in admixture with another form or forms of compound A.