ANTI-CD71 ACTIVATABLE ANTIBODY DRUG CONJUGATES AND METHODS OF USE THEREOF

The invention relates generally to conjugated activatable antibodies that bind CD71 in their active form and methods of making and using these anti-CD71 conjugated activatable antibodies in a variety of therapeutic, diagnostic and prophylactic indications.

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Bibliographische Detailangaben
Hauptverfasser:	BADAGNANI, ILARIA, SINGH, SHWETA, HENRIQUES, TRACY, LEANNA, MARVIN, ROBERT, SERWER, LAURA, PATTERSON, RALSTON, SHERRY, L, BOSE, SAHANA, RICHARDSON, JENNIFER, HOPE, TERRETT, JONATHAN, ALEXANDER, MORGAN-LAPPE, SUSAN, E
Format:	Patent
Sprache:	eng ; srp
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates generally to conjugated activatable antibodies that bind CD71 in their active form and methods of making and using these anti-CD71 conjugated activatable antibodies in a variety of therapeutic, diagnostic and prophylactic indications.