3,4-DIAMINO-6-CHLOROPYRAZINE-2-CARBOXAMIDE COMPOUNDS FOR THE TREATMENT OF ENAC MEDIATED DISEASES

The present invention provides a compound of a formula (I): or a pharmaceutically acceptable salt thereof; a process for preparing such a compound; and to the use of such a compound in the treatment of an ENaC mediated disease state (such as asthma, CF or COPD).

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Bibliographische Detailangaben
Hauptverfasser: KRISTOFFERSSON, ANNA, LUNDKVIST, JOHAN, RUNE, MICHAEL, RIPA, LENA, ELISABETH, BERGLUND, SUSANNE, ELISABETH, HOSSAIN, NAFIZAL, CONNOLLY, STEPHEN, HEMMERLING, MARTIN, SHAMOVSKY, IGOR, NIKITIDIS, GRIGORIOS
Format: Patent
Sprache:eng ; srp
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Beschreibung
Zusammenfassung:The present invention provides a compound of a formula (I): or a pharmaceutically acceptable salt thereof; a process for preparing such a compound; and to the use of such a compound in the treatment of an ENaC mediated disease state (such as asthma, CF or COPD).