AEROSOL FORMULATION FOR THE INHALATION OF BETA AGONISTS

A pharmaceutical formulation, comprising: (a) a compound of formula 1 wherein: R1 is hydrogen, C1-4-alkyl, -O-C1-4-alkyl, or halogen; R2 is hydrogen, C1-4-alkyl, -O-C1-4-alkyl, or halogen; R3 is hydrogen, C1-4-alkyl, -O-C1-4-alkyl, halogen, OH, -O-C1-4-alkylene-COOH, or -O-C1-4-alkylene-COO-C1-4-alk...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	NOWAK, MICHAEL, RADAU, KIRSTEN, NIKLAUS-HUMKE, BARBARA
Format:	Patent
Sprache:	eng ; srp
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	A pharmaceutical formulation, comprising: (a) a compound of formula 1 wherein: R1 is hydrogen, C1-4-alkyl, -O-C1-4-alkyl, or halogen; R2 is hydrogen, C1-4-alkyl, -O-C1-4-alkyl, or halogen; R3 is hydrogen, C1-4-alkyl, -O-C1-4-alkyl, halogen, OH, -O-C1-4-alkylene-COOH, or -O-C1-4-alkylene-COO-C1-4-alkyl; and X− denotes an anion with a single negative charge, or a tautomer, enantiomer, solvate, or hydrate thereof; (b) a second active substance 2 selected from tiotropium salts, oxitropium salts, flutropium salts, ipratropium salts, glycopyrronium salts, and trospium salts, or a tautomer, enantiomer, solvate, or hydrate thereof; (c) at least one pharmacologically acceptable acid; and (d) a solvent selected from water, ethanol, or a mixture of water and ethanol.