ANTIBODIES THAT BIND AND BLOCK TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS-1 (TREM-1)

ANTIBODIES THAT BIND AND BLOCK TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS-1 (TREM-1)

There is provided antibodies that are capable of specifically binding TREM-1 and preventing the activation of TREM-1, a protein expressed on monocytes, macrophages, and neutrophils. Such antibodies find utility in the treatment of individuals with an inflammatory disease.

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Bibliographische Detailangaben
Hauptverfasser: WIBERG, CHARLOTTE, HENRIKSEN, ANETTE, PADKJÆR, SØREN, SALBO, RUNE, GRELL, SUSANNE, NEDERGAARD, READ, CHRISTINE, BRENDER, STENNICKE, VIBEKE, WESTPHAL
Format: Patent
Sprache:eng ; srp
Schlagworte:
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Beschreibung
Zusammenfassung:There is provided antibodies that are capable of specifically binding TREM-1 and preventing the activation of TREM-1, a protein expressed on monocytes, macrophages, and neutrophils. Such antibodies find utility in the treatment of individuals with an inflammatory disease.