DIHYDROPYRIDONE P1 AS FACTOR XIA INHIBITORS
or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective factor XIa inhibitors or dual inhibitors of FXIa and plasma kallikrein. This invention also relates to pharmaceutical compositions comprising thes...
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| creator | FANG, TIANAN PINTO, DONALD, J.P., PINTO EWING, WILLIAM, R SMITH II, LEON, M CORTE, JAMES, R PABBISETTY, KUMAR, B DILGER, ANDREW, K GILLIGAN, PAUL, J YANG, WU WANG, YUFENG |
| description | or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective factor XIa inhibitors or dual inhibitors of FXIa and plasma kallikrein. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating thromboembolic and/or inflammatory disorders using the same. |
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These compounds are selective factor XIa inhibitors or dual inhibitors of FXIa and plasma kallikrein. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating thromboembolic and/or inflammatory disorders using the same.</description><language>eng ; srp</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2017</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20170929&DB=EPODOC&CC=RS&NR=55975B1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25544,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20170929&DB=EPODOC&CC=RS&NR=55975B1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>FANG, TIANAN</creatorcontrib><creatorcontrib>PINTO, DONALD, J.P., PINTO</creatorcontrib><creatorcontrib>EWING, WILLIAM, R</creatorcontrib><creatorcontrib>SMITH II, LEON, M</creatorcontrib><creatorcontrib>CORTE, JAMES, R</creatorcontrib><creatorcontrib>PABBISETTY, KUMAR, B</creatorcontrib><creatorcontrib>DILGER, ANDREW, K</creatorcontrib><creatorcontrib>GILLIGAN, PAUL, J</creatorcontrib><creatorcontrib>YANG, WU</creatorcontrib><creatorcontrib>WANG, YUFENG</creatorcontrib><title>DIHYDROPYRIDONE P1 AS FACTOR XIA INHIBITORS</title><description>or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein all the variables are as defined herein. 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These compounds are selective factor XIa inhibitors or dual inhibitors of FXIa and plasma kallikrein. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating thromboembolic and/or inflammatory disorders using the same.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | DIHYDROPYRIDONE P1 AS FACTOR XIA INHIBITORS |
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