NOVEL COMPOUNDS AS HISTAMINE H3 RECEPTOR LIGANDS

NOVEL COMPOUNDS AS HISTAMINE H3 RECEPTOR LIGANDS

Jedinjenje opšte formule (I):naznačeno time, štokod svakog pojavljivanja, R1 je nezavisno izabran od vodonika, hidroksi, hidroksialkila, halogena, alkila, alkoksi, haloalkila, haloalkoksi, cijano ili -C(O)-NH2;L je alkil iliX je C, O ili N-R2;Y je C ili N;A je -C(O)- ili -CH2;R2 je vodonik, alkil, -...

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Hauptverfasser: JAYARAJAN, PRADEEP, MULLA, MOHMADSADIK ABDULHAMID, DWARAMPUDI, ADI REDDY, SARAF, SANGRAM KESHARI, DESHPANDE, AMOL DINAKAR, JASTI, VENKATESWARLU, NIROGI, RAMAKRISHNA, AHMAD, ISHTIYAQUE, KAMBHAMPATI, RAMASASTRI, SHINDE, ANIL KARBHARI, GANGADASARI, NARASIMHAREDDY, KANDIKERE, VISHWOTTAM NAGARAJ
Format: Patent
Sprache:eng ; srp
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Jedinjenje opšte formule (I):naznačeno time, štokod svakog pojavljivanja, R1 je nezavisno izabran od vodonika, hidroksi, hidroksialkila, halogena, alkila, alkoksi, haloalkila, haloalkoksi, cijano ili -C(O)-NH2;L je alkil iliX je C, O ili N-R2;Y je C ili N;A je -C(O)- ili -CH2;R2 je vodonik, alkil, -C(O)-alkil ili -S(O)2-alkil;"r" je ceo broj u opsegu od 0 do 1;"p" je ceo broj u opsegu od 0 do 3; ili njegova farmaceutski prihvatljiva so.Prijava sadrži još 10 patentnih zahteva. The present invention relates to novel compounds of formula (I), and their pharmaceutically acceptable salts and compositions containing them. The present invention also relates to a process for the preparation of above compounds of formula (I), and their pharmaceutically acceptable salts. The compounds of formula (I) are useful in the treatment of various disorders that are related to Histamine H3 receptors.