PROCESS FOR MAKING 3-SUBSTITUTED 2-AMINO-5-HALOBENZAMIDES

Postupak za pripremu jedinjenja formule 2gde R2 je CH3 ili Cl; i X je Cl ili Br; koji sadrži:dovođenje u dodir jedinjenja formule 4gde R3 je C1-C6 alkil ili C3-C6 alkenil, svaki izborno supstituisan sa do 3 halogena i do 1 fenil;sa fosfor tribromidom.Prijava sadrži još 6 patentnih zahteva. Disclosed is a method for preparing a compound of Formula 1 by contacting compound of Formula 2 with R 1 -NH 2 in the presence of a carboxylic acid, and the compound of Formula 2 may be prepared by contacting a compound of Formula 4 with phosphorus tribromide. wherein R 1 is H, C 1 -C 4 alkyl, cyclopropyl, cyclopropylmethyl or methylcyclopropyl; R 2 is CH 3 or Cl; R 3 is C 1 -C 6 alkyl or C 3 -C 6 alkenyl, each optionally substituted with up to 3 halogen and up to 1 phenyl; and X is Cl or Br.