OXADIAZOLE DERIVATIVES ACTIVE ON SPHINGOSINE-1-PHOSPHATE (SIP)

Jedinjenje formule (I) ili njegova farmaceutski prihvatljiva so:A je fenil ili piridinil;R1 predstavlja do dva supstituenta nezavisno odabrana od halogena, C(1-3)alkoksi, C(1-3)fluoroalkila, cijano, fenil, C(1-3)fluoroalkoksi, C(1-6)alkil i C(3-6)cikloalkila;R2 je vodonik, halogen ili C(1-4)alkil;B...

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Bibliographische Detailangaben
Hauptverfasser:	JOHNSON, CHRISTOPHER, NORBERT, HEER, JAG, PAUL, SKIDMORE, JOHN, HEIGHTMAN, THOMAS, DANIEL, HURST, DAVID, NIGEL, WALL, IAN, DAVID, WITHERINGTON, JASON, DEMONT, EMMANUEL, HUBERT
Format:	Patent
Sprache:	eng ; srp
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Jedinjenje formule (I) ili njegova farmaceutski prihvatljiva so:A je fenil ili piridinil;R1 predstavlja do dva supstituenta nezavisno odabrana od halogena, C(1-3)alkoksi, C(1-3)fluoroalkila, cijano, fenil, C(1-3)fluoroalkoksi, C(1-6)alkil i C(3-6)cikloalkila;R2 je vodonik, halogen ili C(1-4)alkil;B je 7 člani zasićen prsten odabran od slededećih:R3 je vodonik ili (CH2)1-4CO2H;R4 je vodonik;Prijava sadrži još 10 patentnih zahteva. The present invention relates to novel oxadiazole derivatives having pharmacological activity, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders.