METHODS OF TREATING PROSTATE CANCER

The present application relates to treating and/or preventing prostate cancer, including metastatic and/or castrate-resistant prostate cancer, in a subject in need of treatment having particular somatic AR tumor biomarker status, comprising administering a compound of Formula (I), or a pharmaceutically acceptable salt, enantiomer, stereoisomer, solvate, polymorph, isotopic derivative, or prodrug thereof, wherein R1, R2, R3, X1, X2, X3, X4, and n are defined herein. Predmetna prijava se odnosi na lečenje i/ili prevenciju raka prostate, uključujući metastaski i/ili rak prostate otporan na kastrate, kod subjekta kome je potrebno lečenje, a koji ima određeni status biomarkera somatskog AR tumora, i koje obuhvata davanje jedinjenja Formule (I), ili njegove farmaceutski prihvatljive soli, enantiomera, stereoizomera, solvata, polimorfa, izotopskog derivata ili proleka, pri čemu su R1, R2, R3, X1, X2, X3, X4 i n ovde definisani.