CHK-,PDK-AND AKT-INHIBITORY PYRIMIDINES,THEIR PRODUCTION AN USE AS PHARMACEUTICAL AGENTS

This invention relates to pyrimidine derivatives of general formula (I) as inhibitors of kinases, their production as well as their use as medications for treating various diseases. Pronalazak se odnosi na pirimidin derivate opšte formule (I) kao inhibitore kinaza, njihovu proizvodnju kao i njihovu...

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Hauptverfasser: KOCHANNY MONICA, KOSEMUND DIRK, BRYANT JUDI, BOMER ULF, HUWE PETER, ARNAIZ DAMIN, WORTMANN LARS, ESPERLING PETER, PHILLIPS GARY, BUCKMAN BRAD, KUHNKE JOACHIM, FELDMAN RICHARD, SCHAFER MARTINA, ECKLE EMIL, BRIEM HANS, YUAN SHENDONG, KHIM SEOCK KUY
Format: Patent
Sprache:eng ; srp
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Zusammenfassung:This invention relates to pyrimidine derivatives of general formula (I) as inhibitors of kinases, their production as well as their use as medications for treating various diseases. Pronalazak se odnosi na pirimidin derivate opšte formule (I) kao inhibitore kinaza, njihovu proizvodnju kao i njihovu upotrebu za lečenje različitih bolesti.